Sustained high demand for intensive care unit resources for the treatment of burn patients during the COVID-19 pandemic in Northern Germany: A single-centre cross-sectional studyResearch article Published on 2022-07-012022-10-05 Journal: JPRAS Open [Category] 치료법, [키워드] affected Burn burn patient burn patients caused changed Characteristics constant COVID-19 COVID-19 pandemic cross-sectional Descriptive analysis disease transmission Government highlight hospital Injury intensive care intensive care unit introduced majority National national health system occurred occurred less pandemic Patient reduce resource resources Result retrospective SARS-CoV-2 severity social distancing total body Travel Treatment was performed [DOI] 10.1016/j.jpra.2022.07.002 [Article Type] Research article
A simulation of geographic distribution for the emergence of consequential SARS-CoV-2 variant lineages결과적인 SARS-CoV-2 변종 계통의 출현을 위한 지리적 분포 시뮬레이션Article Published on 2022-06-152022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 case COVID-19 cases determine disproportion distribution European country evaluate evaluated expected facilitated Factor genome sequence Genome sequences Lineage Middle East occurred occurred less Occurrence Outbreaks pandemic performed positive correlation produced random Randomly repeated reported SARS-CoV-2 variant Simulation Strains suggested United Kingdom variant [DOI] 10.1038/s41598-022-14308-5 PMC 바로가기 [Article Type] Article
Safety of inactivated SARS-CoV-2 vaccines in patients with allergic diseases알레르기 질환 환자에서 비활성화된 SARS-CoV-2 백신의 안전성Clinical Trial Published on 2022-05-272022-09-12 Journal: Respiratory Research [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] Administered administration affecting allergic allergic disease allergic diseases anti-SARS-CoV-2 IgG Chinese clinical control group diarrhea disease dose event fatigue first dose Frequency General population Hospitalized immunogenicity inactivated incidence injection Local local reaction occurred less Occurrence participant Participants Patient positive IgG antibodies Prevalence reactive registry reported retrospective cohort study Safe Safety SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose Serious Adverse Event Seven skin rash sore throat subjects systemic reaction systemic reactions the patient vaccination vaccine. vertigo [DOI] 10.1186/s12931-022-02054-1 PMC 바로가기 [Article Type] Clinical Trial
History of bariatric surgery and COVID-19 outcomes in patients with type 2 diabetes: Results from the CORONADO studyObservational Study Published on 2022-03-012022-10-05 Journal: Obesity (Silver Spring, Md.) [Category] COVID19(2023년), SARS, 임상, [키워드] Admission age Analysis BMI Clinical outcome Control COVID-19 COVID-19 prognosis CPO death diabete events history Hospitalized Invasive mechanical ventilation no difference obesity occurred less outcome Participants Patient patients with diabete Primary outcome Result SARS-CoV2 Sex T2D type 2 diabete [DOI] 10.1002/oby.23314 PMC 바로가기 [Article Type] Observational Study
Cardiovascular Characteristics and Outcomes of Young Patients with COVID-19Article Published on 2021-11-262022-10-30 Journal: Journal of Cardiovascular Development and Disease [Category] COVID-19, [키워드] cardiovascular complications concerning consecutive patient COVID COVID-19 diabete France heart failure Hospitalized hypertension ICU In-hospital death intensive care less myocarditis obesity occurred less older patients outcome Patient patients patients hospitalized Pericarditis Primary outcome proportion SARS-CoV-2 secondary thrombotic complication transfer with COVID-19 Young [DOI] 10.3390/jcdd8120165 PMC 바로가기 [Article Type] Article
Different dose regimens of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373) in younger and older adults: A phase 2 randomized placebo-controlled trial청소년 및 노인의 SARS-COV-2 재조합 스파이크 단백질 백신 (NVX-COV2373)의 상이한 용량 요법 : 2 상 무작위 위약 대조 시험Clinical Trial Published on 2021-10-012022-08-13 Journal: PLoS Medicine [Category] Biochemistry, MERS, SARS, 임상, 진단, [키워드] 95% CI 95% confidence interval accumulate addition Administered Adults adverse events age Anti-spike Antibody Response assessments assigned composed conducted convalescent sera coronavirus Day dose dose regimen Efficacy Endpoint Enrollment exceeded Follow-up Formica Frequency full-length SARS-CoV-2 geometric mean geometric mean titer geometric mean titers GMTs group groups identify IgG immune persistence immune response immune responses immunogenic immunogenicity Immunoglobulin Immunoglobulin G include inhibitory concentration intensity intramuscular dose lack limitation Matrix-M1 adjuvant median Mild mild to moderate moderate neutralizing antibody Neutralizing antibody response neutralizing antibody responses NVX-CoV2373 occurred less Older Older adults participant Participants Phase 1 Phase 2 Placebo placebo-controlled placebo-controlled trial primary endpoints Protein Randomized randomized placebo-controlled trial Randomly reactogenicity receive Recombinant spike protein regimen researcher respiratory Respiratory Coronavirus robust safety follow-up SARS-CoV-2 second dose second vaccination secondary endpoint seroconversion rate seroconversion rates severity short duration spike glycoprotein spike glycoproteins Spike protein Support The United States These data Tolerability Treatment Trial Trial registration trimeric United States USA vaccination Vaccine vaccine group wild-type virus [DOI] 10.1371/journal.pmed.1003769 PMC 바로가기 [Article Type] Clinical Trial
COVID-19 Pandemic Impact on Respiratory Infectious Diseases in Primary Care Practice in ChildrenPediatrics Published on 2021-09-132022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] acute otitis media age Antibiotics Bacterial Care childhood children Cohort cohorts coronavirus disease COVID-19 COVID-19 pandemic Diseases evaluated Frequency Haemophilus influenzae illness Impact incidence Infection infections during COVID-19 Infectious disease less Moraxella catarrhalis nasopharyngeal nasopharyngeal colonization New York occurred occurred less otitis media pandemic pediatric Practice primary care Prospective Study reduce Regulation respiratory respiratory infection respiratory infections respiratory pathogen returned significant decrease state Streptococcus pneumoniae upper respiratory infection Viral transmission were assessed [DOI] 10.3389/fped.2021.722483 PMC 바로가기 [Article Type] Pediatrics
The Safety and Immunogenicity of the mRNA-BNT162b2 SARS-CoV-2 Vaccine in Hemodialysis PatientsImmunology Published on 2021-06-162022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] age anti-SARS-CoV-2 antibody appear binding activity BNT162b2 chemiluminescent immunoassay Concentration COVID-19 cut-off value dialysis diarrhea dose event expressed fatigue Hemodialysis hepatitis B high risk IgG IgG antibody immunogenicity immunogenicity data Immunosuppression injection international standard LIAISON local reaction median men Mild moderate mRNA vaccine occurred occurred less Patient patients Pfizer/BioNTech positive response reactive Result Safe Safety SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine Seroconversion seropositive severe COVID-19 significantly higher spike IgG Spike protein systemic systemic side effect the patient the WHO Treatment vaccination Vaccine vaccine dose was determined were assessed women [DOI] 10.3389/fimmu.2021.704773 PMC 바로가기 [Article Type] Immunology
Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China2019년 신종 코로나바이러스 감염증(코로나19)과 소아 인플루엔자의 입원 시 임상 양상 비교: 중국 후향적 연구Research Article Published on 2021-04-172022-09-01 Journal: BMC Infectious Diseases [Category] MERS, 진단, [키워드] activated activated partial thromboplastin time Admission C-reactive protein children China Clinical characteristics Clinical data clinical feature coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 patient COVID-19 patients higher odd higher odds Infection Influenza influenza A lymphocyte Lymphocyte count nasal congestion nausea nausea/vomiting neutrophil neutrophil count occurred less on admission partial thromboplastin time Patient pediatric pediatrics procalcitonin prothrombin Prothrombin time Result Retrospective study serum serum C-reactive protein Severe infection supplementary material Symptom symptomatic THROMBOPLASTIN vomiting [DOI] 10.1186/s12879-021-06037-3 PMC 바로가기 [Article Type] Research Article
Is Quarantine for COVID-19 Pandemic Associated with Psychological Burden in Primary Ciliary Dyskinesia?Article Published on 2020-11-032022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Administered burden Care Chest Chronic disorder ciliary dyskinesia Compliance contributed controls COVID-19 COVID-19 pandemic distress emotional Evaluating explained Frequency group healthy controls Italy lockdown mother no significant difference occurred less outbreak parental parental stress participant Patient primary ciliary dyskinesia Psychological Psychological burden psychological Impact Psychological well-being quarantine questionnaire recruited severe acute respiratory syndrome due to coronavirus 2 significantly increased Stress stress level [DOI] 10.3390/ijerph17218099 PMC 바로가기 [Article Type] Article